With inboxes defined, the next step is to enable minor modes that teach particular Emacs modes to link a buffer with a registered inbox. piem currently has libraries to support
For example, if you use notmuch.el to read your mail, you can add
support for applying patches from a Notmuch message buffer by enabling
piem-notmuch-mode (see Applying patches):
Help adding support for other modes, especially other mail clients, is welcome.